Lentiviral Vector
Lentiviral vector upstream and downstream process development and optimization for manufacturing
Improving the Current Industry Standard
OmniaBio’s experienced process development team is adept at scaling-up lentiviral vector (LVV) production by establishing customized processes that are efficient and reliable. Our goal is to create a reproducible, closed, scalable process, improving upon the current industry standard to generate best-in-class recovery rates in downstream purification.
Lentiviral Vector Offerings
- LVV production in serum-free suspension culture
- LVV production using producer or packaging cell lines and transient transfection
- Closed system processing at each unit operation, including in-process testing
- Harvest and clarification steps enabled by scalable filtration technology
- A tailored approach to purification through access to a variety of chromatography resins
- Optimization of sterile filtration for up to 70 per cent recovery at the 1 L scale
Services for Your Project Phase
Process
Development
Experts in optimization to ensure reliable scale-up to produce cell and gene therapies.
GMP
Manufacturing
Our state-of-the-art facility is equipped with the tools and flexibility to manufacture your product at a commercial scale.
Analytical
Development
Providing a robust suite of analytical capabilities that are integrated through your product’s lifecycle to support the development process.
Regulatory
Support
With in-depth knowledge, we can guide you through the regulatory landscape to approval.
