Lentiviral vectors (LVV) are critical tools in both in vivo gene therapy and ex vivo cell therapy manufacturing and have been extensively used for investigational and commercial purposes. Despite existing buffer formulations, there are significant opportunities to develop more robust LVV formulation buffer systems that improve stability and consequently increase recovery of infectious viruses.

In this webinar, we will delve into a detailed case study showcasing our work conducting design of experiments (DoE) to optimize LVV stability:

• Learn how DoE can be utilized to optimize buffer formulations that enhance LVV stability
• Understand key factors affecting LVV stability, including buffer composition, additives, and virus concentration
• Explore testing conditions for analysing short-term and long-term LVV stability